May cause temporary mechanical irritation to exposed eyes, skin or respiratory tract.
Minimize exposure to airborne dust.
Product packaging may contain residue. Do not reuse.
When engineering and/or administrative controls are insufficient to maintain workplace concentrations below the applicable level, the use of appropriate respiratory protection, pursuant to the requirements of OSHA Standards 29 CFR 1910.134 and 29 CFR 1926.103, is recommended. A NIOSH certified respirator with a filter efficiency of at least 95% should be used. The 95% filter efficiency recommendation is based on NIOSH respirator selection logic sequence for exposure to particulates. Selection of filter efficiency (i.e. 95%, 99% or 99.97%) depends on how much filter leakage can be accepted and the concentration of airborne contaminants. Other factors to consider are the NIOSH filter series N, R or P. (N) Not resistant to oil, (R) Resistant to oil and (P) oil Proof. These recommendations are not designed to limit informed choices, provided that respiratory protection decisions comply with 29 CFR 1910.134.
The evaluation of workplace hazards and the identification of appropriate respiratory protection is best performed, on a case by case basis, by a qualified Industrial Hygienist.
Toxicological Data/Epidemiology Data
Lifetime rat inhalation studies of polycrystalline fiber show that at the maximum dose level tested, there was no evidence of lung cancer, lung fibrosis or any other significant adverse effect. Intraperitoneal, intratracheal and intrapleural studies in rats, together with two in vitro tests, have all shown negative results. Despite some study limitations, it is important to note the consistent lack of carcinogenic response in animal studies.
As produced most polycrystalline fibers, including Saffil® and Fibermax®, have fiber diameters too large to be respirable. Numerous scientific studies suggest that the potential toxicity of a respirable fiber is directly related to bio-persistence (the length of time it take for the fiber to clear the lung). Based on limited in-vitro laboratory analysis, which measure the dissolution rate of fibers in simulated lung fluid, polycrystalline fibers are known to be relatively durable.
Data from respiratory surveillance studies are not available for PCW workers. In a small cohort of workers exposed to PCW with historical co-exposures to RCF and other fibers, there was no evidence of interstitial lung disease on chest x-rays nor an accelerated rate of loss of lung function on pulmonary function testing. Symptom responses could not be attributed to or excluded from exposure to PCW as a consequence of the prior fiber exposures.
(e) International Agency for Research on Cancer and National Toxicology Program
In 1988, the International Agency for Research on Cancer (IARC) considered the carcinogenicity of several groups of fibers. One grouping they considered was a poorly defined collection of disparate fiber types [polycrystalline fiber, refractory ceramic fiber (referred to as RCF) and single crystal whiskers] into a broad, single category they termed “ceramic fibers”. The IARC monograph clearly indicated that test data specific to polycrystalline fibers were negative, but according to the IARC classification principles, positive results with other fiber types led to the conclusion that all fibers in the group should be considered as possible human carcinogens (IARC Category 2B). In a subsequent monograph on MMVF (2002), IARC did not specifically re-evaluate polycrystalline fiber. The Annual Report on Carcinogens prepared by the National Toxicology Program (NTP), (latest edition) classified “ceramic fibers (respirable size)” as reasonably anticipated to be carcinogens.
Not classified as dangerous goods under ADR (road), RID (train) or IMDG (ship).